Wenceslau & McCarthy Labs
About Us…
Located in Columbia, SC at the University of South Carolina’s School of Medicine, our lab focuses on better understanding vascular physiology in cardiovascular and metabolic diseases with particular interests in resolving the mechanisms of hypertension. Using state of the art equipment, we study the mechanical and biochemical properties of microvascular tissue collected from mice and rats in order to observe the changes induced by various treatments.
Our lab is a combination space shared and maintained by two principal investigators, Drs. Wenceslau and McCarthy who share similar but distinct research interests. Dr. Wenceslau studies the mechanisms associated with the vascular-immune network in hypertension, metabolic syndrome, and sepsis; whereas, Dr. McCarthy studies dysregulation in cellular recycling (autophagy) and energy sensing and how this relates to deterioration in cardiovascular and metabolic diseases.
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Camilla F. Wenceslau, Ph.D., M.S., FAHA
Principal Investigator
Laboratory of Vascular Biology -
Cameron McCarthy, Ph.D., FAHA
Principal Invesigator
Laboratory of Vascular and Integrative Physiology
Our Techniques
Myography
Cell Culture
Microscopy
In Vivo Hemodynamics
Our Selected Work
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![The face of ketone bodies Tiago Da Costa]()
The O-GlcNAc dichotomy: when does adaptation become pathological?
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Milestone Papers in Signal Transduction Mechanisms of Hypertension and Its Complications
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Vascular dysfunction occurs prior to the onset of amyloid pathology and Aβ plaque deposits colocalize with endothelial cells in the hippocampus of female APPswe/PSEN1dE9 mice
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A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice
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To err, KIR2 that is, on the side of vasodilation in aging
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The janus face of ketone bodies in hypertension
We are grateful to our funding sources and their continued support of our work.
